Ano de Publicação: 2022
AUTORIA
A.S. Ayres, G.A. Bandeira, S.F. Ferraciolli, J.T. Takahashi, R.A. Moreno,
L.F. de Souza Godoy, Y.R. Casal, L.G.C.A. de Lima, F.P. Frasseto, and L.T. Lucato
RESUMO
Neuronal and glioneuronal tumors usually have a benign course and may have typical
imaging characteristics, allowing their diagnosis based on MR imaging findings. The most
common lesions are dysembryoplastic neuroepithelial tumors and gangliogliomas, which
have typical imaging characteristics. The fifth edition of the World Health Organization
Classification of Tumors of the Central Nervous System, recently published in 2021, places
greater emphasis on molecular markers to classify tumors of the CNS, leading to extensive
changes in the classification of tumors, including neuronal and glioneuronal tumors.
The 2021 revision included 3 new tumors types: multinodular and vacuolating neuronal
tumor, diffuse glioneuronal tumor with oligodendroglioma-like features and nuclear clusters
(a provisional type), and myxoid glioneuronal tumor. Following these recent changes
in the World Health Organization classification, we aimed to review the main imaging features
of these lesions in relation to their histopathologic and molecular features.
Learning Objectives: To list the neuronal and glioneuronal tumors; recognize the main
imaging findings and histologic characteristics of neuronal and glioneuronal tumors;
know the typical location of each neuronal and glioneuronal tumor; and become familiar
with the main molecular alterations of neuronal and glioneuronal tumors to better understand
their behavior